Introduction to Mac & Cheese Meatloaf Casserole
Ah, the magic of comfort food! When I think of cozy evenings, nothing warms my heart quite like a Mac & Cheese Meatloaf Casserole. This dish is a delightful blend of juicy meatloaf and creamy mac & cheese, topped with golden melted cheddar. It’s perfect for those busy weeknights when you need a quick solution that still feels like a warm hug. Plus, it’s a surefire way to impress your loved ones, whether it’s a family dinner or a gathering with friends. Trust me, this casserole will become a cherished favorite in your home!
Why You’ll Love This Mac & Cheese Meatloaf Casserole
This Mac & Cheese Meatloaf Casserole is a game-changer in the kitchen! It combines the heartiness of meatloaf with the creamy goodness of mac & cheese, making it a dish everyone will adore. Not only is it easy to prepare, but it also comes together quickly, perfect for those hectic days. Plus, the leftovers are just as delicious, ensuring you can savor this comfort food delight all week long!
Ingredients for Mac & Cheese Meatloaf Casserole
Gathering the right ingredients is the first step to creating this comforting masterpiece. Here’s what you’ll need:
- Ground beef (or a mix of beef & pork): This is the heart of your meatloaf, providing rich flavor and juiciness.
- Breadcrumbs: They help bind the meatloaf together, giving it a lovely texture.
- Onion: Finely chopped, it adds sweetness and depth to the meatloaf.
- Garlic: Minced garlic brings a punch of flavor that elevates the dish.
- Egg: This acts as a binder, helping to hold everything together.
- Milk: A splash of milk keeps the meatloaf moist and tender.
- Ketchup: Adds a touch of sweetness and tang, enhancing the overall flavor.
- Worcestershire sauce: This savory sauce brings umami goodness to the meatloaf.
- Salt & pepper: Essential seasonings that bring out the flavors of all the ingredients.
- Smoked paprika: A hint of smokiness that adds a delightful twist.
- Elbow macaroni (or cavatappi): The star of the mac & cheese, these shapes hold the creamy sauce beautifully.
- Butter: Used in the cheese sauce, it adds richness and flavor.
- All-purpose flour: This is the base for your roux, thickening the cheese sauce.
- Warm milk: Helps create a smooth and creamy cheese sauce.
- Sharp cheddar cheese: The main cheese for that classic mac & cheese flavor.
- mozzarella cheese: Adds a gooey texture that everyone loves.
- Dijon mustard: A little kick that enhances the cheese sauce.
- Extra cheddar cheese: For topping, because who doesn’t love more cheese?
- Fresh thyme or parsley: A sprinkle of herbs for garnish, adding a pop of color and freshness.
For those looking to spice things up, consider adding diced jalapeños to the meatloaf mixture. And if you have cheese preferences, feel free to swap in your favorites! You can find the exact quantities for each ingredient at the bottom of the article, ready for printing.
How to Make Mac & Cheese Meatloaf Casserole
Now that we have our ingredients ready, let’s dive into the fun part—making this Mac & Cheese Meatloaf Casserole! Follow these simple steps, and you’ll have a delicious dish that’s sure to impress.
Step 1: Preheat Oven
First things first, preheat your oven to 375°F (190°C). While it warms up, grease a 9×13” baking dish. This will ensure your casserole doesn’t stick, making cleanup a breeze!
Step 2: Make Meatloaf Base
In a large bowl, combine the ground beef, breadcrumbs, onion, garlic, egg, milk, ketchup, Worcestershire sauce, and seasonings. Mix gently until everything is just combined—overmixing can lead to a tough meatloaf. Press this mixture evenly into the bottom of your greased baking dish. Bake for 20 minutes, and if there’s any excess fat, drain it off. This step is crucial for a juicy meatloaf!
Step 3: Cook Pasta
While the meatloaf is baking, bring a pot of salted water to a boil. Cook the macaroni until it’s al dente, which usually takes about 7-8 minutes. Drain the pasta and set it aside. This will be the creamy heart of your casserole!
Step 4: Make Cheese Sauce
In a saucepan, melt the butter over medium heat. Once melted, whisk in the flour to create a roux. This will help thicken your cheese sauce. Gradually whisk in the warm milk, stirring until the mixture is smooth and thickened. Now, stir in the cheddar, mozzarella, Dijon mustard, salt, and pepper until it’s all creamy and delicious. This cheese sauce is the magic that ties everything together!
Step 5: Assemble Casserole
Mix the cooked pasta with the cheese sauce until it’s well coated. Spread half of this mac & cheese mixture over the baked meatloaf base. Then, add the remaining mac & cheese on top. To finish, sprinkle extra cheddar cheese over everything. Because let’s be honest, more cheese is always a good idea!
Step 6: Bake
Return the casserole to the oven and bake uncovered for 25–30 minutes. You want it to be golden and bubbly. For an extra crispy top, broil it for 2–3 minutes at the end. Just keep an eye on it so it doesn’t burn!
Step 7: Rest & Serve
Once it’s out of the oven, let the casserole rest for about 10 minutes. This helps it set up a bit, making it easier to slice into squares. Garnish with fresh thyme or parsley for a pop of color and flavor. Now, dig in and enjoy your comforting creation!

Tips for Success
- Don’t overmix the meatloaf mixture; it can make it tough.
- Use warm milk for the cheese sauce to ensure a smooth texture.
- Feel free to customize the cheese blend to suit your taste.
- Let the casserole rest before slicing; it helps with serving.
- For a spicier kick, add diced jalapeños to the meatloaf.
Equipment Needed
- 9×13” baking dish: Essential for assembling your casserole. A similar-sized dish works too.
- Large mixing bowl: Perfect for combining the meatloaf ingredients. Any large bowl will do.
- Saucepan: Needed for making the cheese sauce. A deep skillet can also work.
- Whisk: Great for mixing the cheese sauce. A fork can be a handy alternative.
- Pot for boiling pasta: Any large pot will suffice for cooking the macaroni.
Variations
- Turkey or Chicken Meatloaf: Swap out the beef for ground turkey or chicken for a lighter option.
- Vegetarian Version: Use lentils or black beans in place of meat, and add extra veggies like bell peppers or spinach.
- Different Cheeses: Experiment with gouda, pepper jack, or even blue cheese for a unique flavor twist.
- Gluten-Free Option: Use gluten-free breadcrumbs and pasta to make this dish suitable for gluten-sensitive eaters.
- Spicy Kick: Add diced jalapeños or a splash of hot sauce to the meatloaf mixture for some heat.
Serving Suggestions
- Fresh Salad: Pair your casserole with a crisp green salad for a refreshing contrast.
- Garlic Bread: Serve with warm garlic bread to soak up any cheesy goodness.
- Wine Pairing: A glass of red wine complements the rich flavors beautifully.
- Presentation: Garnish with fresh herbs for a pop of color and flavor.
FAQs about Mac & Cheese Meatloaf Casserole
Can I make Mac & Cheese Meatloaf Casserole ahead of time?
Absolutely! You can prepare the casserole in advance and store it in the refrigerator before baking. Just cover it tightly with plastic wrap or aluminum foil. When you’re ready to bake, remove the cover and pop it in the oven. You may need to add a few extra minutes to the baking time.
What can I substitute for ground beef in this recipe?
If you’re looking for alternatives, ground turkey or chicken works well. You can also use a mix of beef and pork for added flavor. For a vegetarian option, consider using lentils or black beans instead of meat.
How do I store leftovers of Mac & Cheese Meatloaf Casserole?
Leftovers can be stored in an airtight container in the refrigerator for up to 3-4 days. Just reheat in the oven or microwave until warmed through. Trust me, it’s just as delicious the next day!
Can I freeze this casserole?
Yes, you can freeze the Mac & Cheese Meatloaf Casserole! Just make sure it’s completely cooled before wrapping it tightly in plastic wrap and aluminum foil. It can be frozen for up to 3 months. Thaw it in the fridge overnight before baking.
What sides pair well with this casserole?
This casserole is hearty on its own, but it pairs beautifully with a fresh salad or some garlic bread. A side of steamed vegetables can also add a nice touch of color and nutrition to your meal!
Final Thoughts
Creating this Mac & Cheese Meatloaf Casserole is more than just cooking; it’s about bringing warmth and joy to your table. The combination of flavors and textures creates a dish that feels like a hug on a plate. Whether you’re sharing it with family or enjoying it solo, each bite is a reminder of home and comfort. Plus, the smiles it brings are priceless! So, roll up your sleeves, gather your loved ones, and dive into this delightful casserole. Trust me, it will quickly become a cherished recipe in your kitchen, just like it is in mine!
Print
Mac & Cheese Meatloaf Casserole: A Comfort Food Delight!
- Total Time: 1 hr 25 min
- Yield: 6–8 servings 1x
- Diet: Comfort Food
Description
A hearty comfort food classic—juicy meatloaf layered with creamy mac & cheese and topped with golden melted cheddar.
Ingredients
- 1 ½ lbs ground beef (or a mix of beef & pork)
- 1 cup breadcrumbs
- 1 small onion, finely chopped
- 2 garlic cloves, minced
- 1 large egg
- ½ cup milk
- 2 tbsp ketchup
- 1 tbsp Worcestershire sauce
- 1 tsp salt
- ½ tsp black pepper
- ½ tsp smoked paprika
- 1 lb elbow macaroni (or cavatappi)
- 4 tbsp butter
- ¼ cup all-purpose flour
- 4 cups milk (warm)
- 3 cups sharp cheddar cheese, shredded
- 1 cup mozzarella cheese, shredded
- 1 tsp Dijon mustard
- Salt & pepper to taste
- 1 cup cheddar cheese, shredded (for topping)
- Fresh thyme or parsley for garnish
Instructions
- Preheat Oven – Heat to 375°F (190°C). Grease a 9×13” baking dish.
- Make Meatloaf Base: In a large bowl, combine ground beef, breadcrumbs, onion, garlic, egg, milk, ketchup, Worcestershire, and seasonings. Mix gently until combined (don’t overmix). Press mixture evenly into the bottom of the baking dish. Bake for 20 minutes. Drain excess fat if needed.
- Cook Pasta: While meatloaf bakes, cook macaroni in salted water until al dente. Drain and set aside.
- Make Cheese Sauce: In a saucepan, melt butter. Whisk in flour to form a roux. Slowly whisk in warm milk until smooth and thickened. Stir in cheddar, mozzarella, Dijon, salt & pepper until creamy.
- Assemble Casserole: Mix cooked pasta with cheese sauce. Spread half of the mac & cheese over baked meatloaf base. Add remaining mac & cheese on top. Sprinkle with extra cheddar cheese.
- Bake: Return to oven and bake uncovered for 25–30 minutes until golden and bubbly. For extra crispiness, broil 2–3 minutes at the end.
- Rest & Serve: Let casserole rest 10 minutes before slicing into squares. Garnish with fresh thyme or parsley.
Notes
- For a spicier kick, add some diced jalapeños to the meatloaf mixture.
- Feel free to substitute the cheeses based on your preference.
- This dish can be made ahead of time and stored in the refrigerator before baking.
- Prep Time: 25 min
- Cook Time: 50–55 min
- Category: Casserole
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 serving
- Calories: 550
- Sugar: 4g
- Sodium: 800mg
- Fat: 30g
- Saturated Fat: 15g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 45g
- Fiber: 2g
- Protein: 30g
- Cholesterol: 100mg

